rala Antikörper (AA 1-203) (HRP)

Produktnummer ABIN7167393

Der Kaninchen Polyklonal Anti-rala-Antikörper wurde für ELISA validiert. Er ist geeignet, rala in Proben von Human zu detektieren.

Kurzübersicht für rala Antikörper (AA 1-203) (HRP) (ABIN7167393)

Target: rala (Ras-related Protein Ral-A (rala))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser rala Antikörper ist konjugiert mit HRP

Applikation: ELISA

Produktdetails anti-rala Antikörper (HRP)

Bindungsspezifität: AA 1-203

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Ras-related protein Ral-A protein (1-203AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu rala

Target: rala (Ras-related Protein Ral-A (rala))

Andere Bezeichnung: RALA

Hintergrund:

Background: Multifunctional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. Accomplishes its multiple functions by interacting with distinct downstream effectors. Acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles. Plays a role in the early stages of cytokinesis and is required to tether the exocyst to the cytokinetic furrow. The RALA-exocyst complex regulates integrin-dependent membrane raft exocytosis and growth signaling. Key regulator of LPAR1 signaling and competes with GRK2 for binding to LPAR1 thus affecting the signaling properties of the receptor. Required for anchorage-independent proliferation of transformed cells.

Aliases: MGC48949 antibody, Ral a antibody, Ral A protein antibody, RAL antibody, RALA antibody, RALA_HUMAN antibody, Ras family small GTP binding protein RALA antibody, RAS like protein A antibody, Ras related protein RalA antibody, Ras-related protein Ral-A antibody, v ral simian leukemia viral oncogene homolog A (ras related) antibody, v ral simian leukemia viral oncogene homolog A antibody

UniProt: P11233

Pathways: Neurotrophin Signalübertragung, SARS-CoV-2 Protein Interaktom