RAB35 Antikörper (AA 1-201)

Produktnummer ABIN7167302

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch RAB35 in ELISA, IHC und IF. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für RAB35 Antikörper (AA 1-201) (ABIN7167302)

Target: RAB35 (RAB35, Member RAS Oncogene Family (RAB35))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAB35 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-RAB35 Antikörper

Bindungsspezifität: AA 1-201

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Ras-related protein Rab-35 protein (1-201AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu RAB35

Target: RAB35 (RAB35, Member RAS Oncogene Family (RAB35))

Andere Bezeichnung: RAB35

Hintergrund:

Background: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab is involved in the process of endocytosis and is an essential rate-limiting regulator of the fast recycling pathway back to the plasma membrane. During cytokinesis, required for the postfurrowing terminal steps, namely for intercellular bridge stability and abscission, possibly by controlling phosphatidylinositol 4,5-bis phosphate (PIP2) and SEPT2 localization at the intercellular bridge. May indirectly regulate neurite outgrowth. Together with TBC1D13 may be involved in regulation of insulin-induced glucose transporter SLC2A4/GLUT4 translocation to the plasma membrane in adipocytes.

Aliases: GTP binding protein RAY antibody, GTP-binding protein RAY antibody, H ray antibody, OTTHUMP00000240256 antibody, OTTHUMP00000240257 antibody, OTTHUMP00000240258 antibody, OTTHUMP00000240259 antibody, RAB1C antibody, Rab35 antibody, RAB35 member RAS oncogene family antibody, RAB35, member RAS oncogene family antibody, RAB35_HUMAN antibody, Ras related protein rab 1c (GTP binding protein ray) antibody, Ras related protein Rab 1C antibody, Ras related protein Rab35 antibody, Ras-related protein Rab-1C antibody, Ras-related protein Rab-35 antibody, RAY antibody

UniProt: Q15286