RAB35 Antikörper (Internal Region)

Produktnummer ABIN6264573

Produktdetails anti-RAB35 Antikörper

Target: RAB35 (RAB35, Member RAS Oncogene Family (RAB35))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAB35 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: RAB35 Antibody detects endogenous levels of total RAB35.

Homologie: Pig,Bovine,Horse,Rabbit,Dog,Chicken,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human RAB35, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu RAB35

Target: RAB35 (RAB35, Member RAS Oncogene Family (RAB35))

Andere Bezeichnung: RAB35 (RAB35 Produkte)

Synonyme: h-ray antikoerper, rab1c antikoerper, MGC69101 antikoerper, ray antikoerper, MGC76044 antikoerper, dZ146N9.2 antikoerper, zgc:100812 antikoerper, si:busm1-146n9.2 antikoerper, H-ray antikoerper, RAB1C antikoerper, RAY antikoerper, 9530019H02Rik antikoerper, AU040256 antikoerper, RAB35, member RAS oncogene family S homeolog antikoerper, RAB35, member RAS oncogene family antikoerper, RAB35, member RAS oncogene family b antikoerper, rab35.S antikoerper, rab35 antikoerper, rab35b antikoerper, RAB35 antikoerper, Rab35 antikoerper

Hintergrund:

Description: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab is involved in the process of endocytosis and is an essential rate-limiting regulator of the fast recycling pathway back to the plasma membrane. During cytokinesis, required for the postfurrowing terminal steps, namely for intercellular bridge stability and abscission, possibly by controlling phosphatidylinositol 4,5-bis phosphate (PIP2) and SEPT2 localization at the intercellular bridge. May indirectly regulate neurite outgrowth. Together with TBC1D13 may be involved in regulation of insulin-induced glucose transporter SLC2A4/GLUT4 translocation to the plasma membrane in adipocytes.

Gene: RAB35

Molekulargewicht: 23 kDa

Gen-ID: 11021

UniProt: Q15286