RASSF5 Antikörper (AA 1-265)

Produktnummer ABIN7167138

Der Kaninchen Polyklonal Anti-RASSF5-Antikörper wurde für WB, ELISA und IHC validiert. Er ist geeignet, RASSF5 in Proben von Human zu detektieren.

Kurzübersicht für RASSF5 Antikörper (AA 1-265) (ABIN7167138)

Target: RASSF5 (Ras Association (RalGDS/AF-6) Domain Family Member 5 (RASSF5))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RASSF5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-RASSF5 Antikörper

Bindungsspezifität: AA 1-265

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Ras association domain-containing protein 5 protein (1-265AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu RASSF5

Target: RASSF5 (Ras Association (RalGDS/AF-6) Domain Family Member 5 (RASSF5))

Andere Bezeichnung: RASSF5

Hintergrund:

Background: Potential tumor suppressor. Seems to be involved in lymphocyte adhesion by linking RAP1A activation upon T-cell receptor or chemokine stimulation to integrin activation. Isoform 2 stimulates lymphocyte polarization and the patch-like distribution of ITGAL/LFA-1, resulting in an enhanced adhesion to ICAM1. Together with RAP1A may participate in regulation of microtubule growth. The association of isoform 2 with activated RAP1A is required for directional movement of endothelial cells during wound healing. May be involved in regulation of Ras apoptotic function. The RASSF5-STK4/MST1 complex may mediate HRAS and KRAS induced apoptosis.

Aliases: Maxp 1 antibody, MAXP1 antibody, MGC10823 antibody, MGC17344 antibody, New ras effector 1 antibody, NORE 1 antibody, NORE1 antibody, NORE1A antibody, NORE1B antibody, Novel Ras effector 1 antibody, RAP1 Binding Protein antibody, RAPL antibody, Ras association (RalGDS/AF 6) domain family 5 antibody, Ras association (RalGDS/AF 6) domain family member 5 antibody, Ras association domain containing family protein 5 antibody, Ras association domain-containing protein 5 antibody, Ras effector like protein antibody, RASF5_HUMAN antibody, RASSF 3 antibody, RASSF 5 antibody, RASSF3 antibody, RASSF5 antibody, Regulator for cell adhesion and polarization enriched in lymphoid tissue antibody, Regulator for cell adhesion and polarization enriched in lymphoid tissues antibody, Tumor suppressor RASSF3 antibody

UniProt: Q8WWW0

Pathways: T-Zell Rezeptor Signalweg