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RSPO1 Antikörper (AA 21-263)

RSPO1 Reaktivität: Human IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7166935
  • Target Alle RSPO1 Antikörper anzeigen
    RSPO1 (R-Spondin 1 (RSPO1))
    Bindungsspezifität
    • 15
    • 7
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    AA 21-263
    Reaktivität
    • 45
    • 40
    • 35
    • 15
    • 15
    • 15
    • 15
    • 15
    Human
    Wirt
    • 48
    • 6
    • 1
    Kaninchen
    Klonalität
    • 49
    • 6
    Polyklonal
    Konjugat
    • 24
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Dieser RSPO1 Antikörper ist unkonjugiert
    Applikation
    • 38
    • 15
    • 13
    • 11
    • 11
    • 7
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    Immunohistochemistry (IHC), ELISA
    Kreuzreaktivität
    Human
    Aufreinigung
    Antigen Affinity Purified
    Immunogen
    Recombinant Human R-spondin-1 protein (21-263AA)
    Isotyp
    IgG
    Top Product
    Discover our top product RSPO1 Primärantikörper
  • Applikationshinweise
    Recommended dilution: IHC:1:20-1:200,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    RSPO1 (R-Spondin 1 (RSPO1))
    Andere Bezeichnung
    RSPO1 (RSPO1 Produkte)
    Synonyme
    RGD1565558 antikoerper, CRISTIN3 antikoerper, RSPO antikoerper, R-spondin antikoerper, Rspondin antikoerper, wu:fj81e05 antikoerper, zgc:92153 antikoerper, R-spondin 1 antikoerper, Rspo1 antikoerper, RSPO1 antikoerper, LOC100049655 antikoerper, rspo1 antikoerper
    Hintergrund

    Background: Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors. Upon binding to LGR4-6 (LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. Also regulates the canonical Wnt/beta-catenin-dependent pathway and non-canonical Wnt signaling by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway. Acts as a ligand for frizzled FZD8 and LRP6. May negatively regulate the TGF-beta pathway. Has a essential roles in ovary determination.

    Aliases: CRISTIN3, FLJ40906, hRspo1, R spondin homolog, R spondin homolog (Xenopus laevis), R spondin1, R-spondin-1, Roof plate specific spondin, Roof plate-specific spondin-1, RP11-566C13.1, RSPO, Rspo1, RSPO1_HUMAN

    UniProt
    Q2MKA7
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