RSPO1 Antikörper (AA 21-263)
Kurzübersicht für RSPO1 Antikörper (AA 21-263) (ABIN7166935)
Target
Alle RSPO1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 21-263
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Kreuzreaktivität
- Human
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Aufreinigung
- Antigen Affinity Purified
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Immunogen
- Recombinant Human R-spondin-1 protein (21-263AA)
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Isotyp
- IgG
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anti-R-Spondin 1 (RSPO1) (AA 21-135) antibody
RSPO1 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-R-Spondin 1 (RSPO1) (AA 21-135) antibodyRSPO1 Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-R-Spondin 1 (RSPO1) (AA 136-262) antibodyRSPO1 Reaktivität: Ratte WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-R-Spondin 1 (RSPO1) (AA 21-263) antibodyRSPO1 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-R-Spondin 1 (RSPO1) antibodyRSPO1 Reaktivität: Human ELISA Wirt: Maus Monoclonal 7A6 unconjugated
anti-R-Spondin 1 (RSPO1) antibodyRSPO1 Reaktivität: Human, Ratte, Maus WB, IF (p), IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-R-Spondin 1 (RSPO1) (AA 206-240) antibodyRSPO1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB54226 unconjugated
anti-R-Spondin 1 (RSPO1) (AA 21-135) antibodyRSPO1 Reaktivität: Ratte WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-R-Spondin 1 (RSPO1) (N-Term) antibodyRSPO1 Reaktivität: Human, Ratte, Maus WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-R-Spondin 1 (RSPO1) (N-Term) antibodyRSPO1 Reaktivität: Human, Ratte, Maus WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- Recommended dilution: IHC:1:20-1:200,
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- RSPO1 (R-Spondin 1 (RSPO1))
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Andere Bezeichnung
- RSPO1
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Hintergrund
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Background: Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors. Upon binding to LGR4-6 (LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. Also regulates the canonical Wnt/beta-catenin-dependent pathway and non-canonical Wnt signaling by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway. Acts as a ligand for frizzled FZD8 and LRP6. May negatively regulate the TGF-beta pathway. Has a essential roles in ovary determination.
Aliases: CRISTIN3, FLJ40906, hRspo1, R spondin homolog, R spondin homolog (Xenopus laevis), R spondin1, R-spondin-1, Roof plate specific spondin, Roof plate-specific spondin-1, RP11-566C13.1, RSPO, Rspo1, RSPO1_HUMAN
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UniProt
- Q2MKA7
Target
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