MAS1 Antikörper (AA 246-325)
Kurzübersicht für MAS1 Antikörper (AA 246-325) (ABIN7166484)
Target
Alle MAS1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 246-325
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Kreuzreaktivität
- Human
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Aufreinigung
- Antigen Affinity Purified
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Immunogen
- Recombinant Human Proto-oncogene Mas protein (246-325AA)
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Isotyp
- IgG
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Applikationshinweise
- Recommended dilution: IHC:1:20-1:200,
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- MAS1 (MAS1 Oncogene (MAS1))
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Andere Bezeichnung
- MAS1
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Hintergrund
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Background: Receptor for angiotensin 1-7 (By similarity). Acts specifically as a functional antagonist of AGTR1 (angiotensin-2 type 1 receptor), although it up-regulates AGTR1 receptor levels. Positive regulation of AGTR1 levels occurs through activation of the G-proteins GNA11 and GNAQ, and stimulation of the protein kinase C signaling cascade. The antagonist effect on AGTR1 function is probably due to AGTR1 being physically altered by MAS1.
Aliases: MAS antibody, MAS proto oncogene antibody, Mas-related G protein-coupled receptor A antibody, MAS_HUMAN antibody, Mas1 antibody, MAS1 oncogene antibody, MAS1 proto-oncogene, G protein-coupled receptor antibody, MGRA antibody, Proto-oncogene Mas antibody
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UniProt
- P04201
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Pathways
- ACE Inhibitor Pathway, Regulation of Carbohydrate Metabolic Process
Target
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