SBNO2 Antikörper (AA 6-146) (Biotin)

Produktnummer ABIN7166167

Dieses Anti-SBNO2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von SBNO2 in ELISA. Geeignet für Human.

Kurzübersicht für SBNO2 Antikörper (AA 6-146) (Biotin) (ABIN7166167)

Target: SBNO2 (Strawberry Notch Homolog 2 (SBNO2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SBNO2 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Produktdetails anti-SBNO2 Antikörper (Biotin)

Bindungsspezifität: AA 6-146

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Protein strawberry notch homolog 2 protein (6-146AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu SBNO2

Target: SBNO2 (Strawberry Notch Homolog 2 (SBNO2))

Andere Bezeichnung: SBNO2

Hintergrund:

Background: Acts as a transcriptional coregulator, that can have both coactivator and corepressor functions. Inhibits the DCSTAMP-repressive activity of TAL1, hence enhancing the access of the transcription factor MITF to the DC-STAMP promoter in osteoclast. Plays a role in bone homeostasis, required as a positive regulator in TNFSF11//RANKL-mediated osteoclast fusion via a DCSTAMP-dependent pathway. May also be required in the regulation of osteoblast differentiation (By similarity). Involved in the transcriptional corepression of NF-kappaB in macrophages (PubMed:18025162). Plays a role as a regulator in the proinflammatory cascade (PubMed:18025162).

Aliases: SBNO2 antibody, KIAA0963Protein strawberry notch homolog 2 antibody

UniProt: Q9Y2G9