SBNO2 Antikörper (AA 6-146)
SBNO2
Reaktivität: Human
ELISA, IF
Wirt: Kaninchen
Polyclonal
unconjugated
1 image
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- Target Alle SBNO2 Antikörper anzeigen
- SBNO2 (Strawberry Notch Homolog 2 (SBNO2))
- Bindungsspezifität
- AA 6-146
- Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SBNO2 Antikörper ist unkonjugiert
- Applikation
- ELISA, Immunofluorescence (IF)
- Kreuzreaktivität
- Human
- Aufreinigung
- >95%, Protein G purified
- Immunogen
- Recombinant Human Protein strawberry notch homolog 2 protein (6-146AA)
- Isotyp
- IgG
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- Applikationshinweise
- Recommended dilution: IF:1:20-1:200,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- SBNO2 (Strawberry Notch Homolog 2 (SBNO2))
- Andere Bezeichnung
- SBNO2 (SBNO2 Produkte)
- Synonyme
- KIAA0963 antikoerper, SNO antikoerper, STNO antikoerper, BC019206 antikoerper, F730040C21 antikoerper, Sno antikoerper, Stno antikoerper, strawberry notch homolog 2 antikoerper, strawberry notch homolog 2 (Drosophila) antikoerper, SBNO2 antikoerper, Sbno2 antikoerper
- Hintergrund
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Background: Acts as a transcriptional coregulator, that can have both coactivator and corepressor functions. Inhibits the DCSTAMP-repressive activity of TAL1, hence enhancing the access of the transcription factor MITF to the DC-STAMP promoter in osteoclast. Plays a role in bone homeostasis, required as a positive regulator in TNFSF11//RANKL-mediated osteoclast fusion via a DCSTAMP-dependent pathway. May also be required in the regulation of osteoblast differentiation (By similarity). Involved in the transcriptional corepression of NF-kappaB in macrophages (PubMed:18025162). Plays a role as a regulator in the proinflammatory cascade (PubMed:18025162).
Aliases: SBNO2 antibody, KIAA0963Protein strawberry notch homolog 2 antibody
- UniProt
- Q9Y2G9
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