MDM4-binding Protein Antikörper (AA 208-306)
Kurzübersicht für MDM4-binding Protein Antikörper (AA 208-306) (ABIN7165802)
Target
Alle MDM4-binding Protein (MDM4) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 208-306
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Kreuzreaktivität
- Human, Maus
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Aufreinigung
- >95%, Protein G purified
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Immunogen
- Recombinant Human Protein Mdm4 protein (208-306AA)
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Isotyp
- IgG
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Applikationshinweise
- Recommended dilution: WB:1:500-1:5000,
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- MDM4-binding Protein (MDM4) (Mdm4-binding Protein (MDM4))
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Andere Bezeichnung
- MDM4
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Hintergrund
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Background: Inhibits p53/TP53- and TP73/p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Inhibits degradation of MDM2. Can reverse MDM2-targeted degradation of TP53 while maintaining suppression of TP53 transactivation and apoptotic functions.
Aliases: DKFZp781B1423 antibody, Double minute 4 antibody, Double minute 4 human homolog of p53 binding protein antibody, Double minute 4 protein antibody, HDMX antibody, MDM 4 antibody, Mdm2 like p53 binding protein antibody, Mdm2-like p53-binding protein antibody, MDM4 antibody, Mdm4 p53 binding protein homolog mouse antibody, Mdm4 protein antibody, MDM4 related protein 1 antibody, Mdm4 transformed 3T3 cell double minute 4 antibody, Mdm4 transformed 3T3 cell double minute 4 p53 binding protein antibody, Mdm4 transformed 3T3 cell double minute 4 p53 binding protein mouse antibody, MDM4_HUMAN antibody, Mdmx protein antibody, MGC132766 antibody, Mouse double minute 4 homolog antibody, Mouse double minute 4 human homolog of p53 binding protein antibody, MRP 1 antibody, MRP1 antibody, p53 binding protein antibody, p53 BINDING PROTEIN MDM4 antibody, p53-binding protein Mdm4 antibody, Protein Mdm4 antibody, Protein Mdmx antibody
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UniProt
- O15151
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Pathways
- Zellzyklus
Target
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