Prohibitin 2 Antikörper (AA 1-299)
Kurzübersicht für Prohibitin 2 Antikörper (AA 1-299) (ABIN7164708)
Target
Alle Prohibitin 2 (PHB2) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1-299
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Kreuzreaktivität
- Human
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Aufreinigung
- Antigen Affinity Purified
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Immunogen
- Recombinant Human Prohibitin-2 protein (1-299AA)
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Isotyp
- IgG
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Applikationshinweise
- Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Prohibitin 2 (PHB2)
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Andere Bezeichnung
- PHB2
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Hintergrund
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Background: Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging.
Aliases: B cell receptor associated protein BAP37 antibody, B-cell receptor-associated protein BAP37 antibody, BAP antibody, Bap37 antibody, BCAP 37 antibody, D prohibitin antibody, D-prohibitin antibody, p22 antibody, Phb2 antibody, PHB2_HUMAN antibody, PNAS 141 antibody, Prohibitin 2 antibody, Prohibitin-2 antibody, Repressor of estrogen receptor activity antibody
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UniProt
- Q99623
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Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
Target
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