Lamin A/C Antikörper (AA 385-572)

Produktnummer ABIN7164247

Dieses Anti-Lamin A/C-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Lamin A/C in WB, IHC, ELISA und IF. Geeignet für Human.

Kurzübersicht für Lamin A/C Antikörper (AA 385-572) (ABIN7164247)

Target: Lamin A/C (LMNA)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Lamin A/C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-Lamin A/C Antikörper

Bindungsspezifität: AA 385-572

Kreuzreaktivität: Human, Ratte

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Prelamin-A/C protein (385-572AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:1000-1:5000, IHC:1:200-1:500, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu Lamin A/C

Target: Lamin A/C (LMNA)

Andere Bezeichnung: LMNA

Hintergrund:

Background: Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. Lamin A and C are present in equal amounts in the lamina of mammals. Plays an important role in nuclear assembly, chromatin organization, nuclear membrane and telomere dynamics. Required for normal development of peripheral nervous system and skeletal muscle and for muscle satellite cell proliferation. Required for osteoblastogenesis and bone formation. Also prevents fat infiltration of muscle and bone marrow, helping to maintain the volume and strength of skeletal muscle and bone.

Aliases: 70 kDa lamin antibody, Cardiomyopathy dilated 1A (autosomal dominant) antibody, CDCD1 antibody, CDDC antibody, CMD1A antibody, CMT2B1 antibody, EMD2 antibody, FPL antibody, FPLD antibody, FPLD2 antibody, HGPS antibody, IDC antibody, Lamin A antibody, Lamin A/C antibody, Lamin A/C like 1 antibody, Lamin antibody, Lamin C antibody, lamin-a antibody, Lamin-A/C antibody, LDP1 antibody, LFP antibody, LGMD1B antibody, Limb girdle muscular dystrophy 1B (autosomal dominant) antibody, LMN 1 antibody, LMN A antibody, LMN C antibody, LMN1 antibody, LMNA antibody, LMNA_HUMAN antibody, LMNC antibody, LMNL1 antibody, Prelamin A/C antibody, PRO1 antibody, Renal carcinoma antigen NY REN 32 antibody, Renal carcinoma antigen NY-REN-32 antibody, Renal carcinoma antigen NYREN32 antibody

UniProt: P02545

Pathways: Apoptose, Caspase Kaskade in der Apoptose, ER-Nucleus Signaling, Protein targeting to Nucleus