NOXA Antikörper (AA 1-136)
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- Target Alle NOXA (PMAIP1) Antikörper anzeigen
- NOXA (PMAIP1) (Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1))
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Bindungsspezifität
- AA 1-136
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser NOXA Antikörper ist unkonjugiert
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Applikation
- ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)
- Kreuzreaktivität
- Human
- Aufreinigung
- >95%, Protein G purified
- Immunogen
- Recombinant Human Phorbol-12-myristate-13-acetate-induced protein 1 protein (1-136AA)
- Isotyp
- IgG
- Top Product
- Discover our top product PMAIP1 Primärantikörper
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anti-Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1) (AA 1-54) antibody
PMAIP1 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1) (AA 1-54) antibodyPMAIP1 Reaktivität: Human ELISA, FACS Wirt: Maus Monoclonal 1A2D3 unconjugated
anti-Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1) antibodyPMAIP1 Reaktivität: Human WB, IF, IHC, FACS Wirt: Maus Monoclonal 114C307-1 unconjugated
anti-Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1) (AA 1-136) antibodyPMAIP1 Reaktivität: Human WB Wirt: Maus Polyclonal unconjugated
anti-Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1) (Internal Region) antibodyVerified PMAIP1 Reaktivität: Human WB, ELISA Wirt: Ziege Polyclonal unconjugated
anti-Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1) (N-Term) antibodyPMAIP1 Reaktivität: Human, Maus, Ratte WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- NOXA (PMAIP1) (Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1))
- Andere Bezeichnung
- PMAIP1 (PMAIP1 Produkte)
- Hintergrund
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Background: Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1 (By similarity). Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1.
Aliases: Adult T cell leukemia derived PMA responsive antibody, APR antibody, APR_HUMAN antibody, ATL-derived antibody, Immediate early response protein APR antibody, Immediate-early-response protein APR antibody, NOXA antibody, Phorbol 12 myristate 13 acetate induced protein 1 antibody, Phorbol-12-myristate-13-acetate-induced protein 1 antibody, PMA induced protein 1 antibody, PMA-induced protein 1 antibody, PMA-responsive gene antibody, Pmaip1 antibody, Protein Noxa antibody
- UniProt
- Q13794
- Pathways
- p53 Signalweg, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus
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