PPARG Antikörper (AA 1-477)

Produktnummer ABIN7163013

Der Kaninchen Polyklonal Anti-PPARG-Antikörper wurde für IHC, ELISA und IF validiert. Er ist geeignet, PPARG in Proben von Human zu detektieren.

Kurzübersicht für PPARG Antikörper (AA 1-477) (ABIN7163013)

Target: PPARG (Peroxisome Proliferator-Activated Receptor gamma (PPARG))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPARG Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-PPARG Antikörper

Bindungsspezifität: AA 1-477

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Peroxisome proliferator-activated receptor gamma protein (1-477AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu PPARG

Target: PPARG (Peroxisome Proliferator-Activated Receptor gamma (PPARG))

Andere Bezeichnung: PPARG

Hintergrund:

Background: Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut homeostasis by suppressing NF-kappa-B-mediated proinflammatory responses.

Aliases: CIMT1 antibody, GLM1 antibody, NR1C3 antibody, Nuclear receptor subfamily 1 group C member 3 antibody, OTTHUMP00000185032 antibody, OTTHUMP00000185036 antibody, Peroxisome proliferator activated nuclear receptor gamma variant 1 antibody, Peroxisome proliferator activated receptor gamma 1 antibody, Peroxisome Proliferator Activated Receptor gamma antibody, Peroxisome proliferator-activated receptor gamma antibody, PPAR gamma antibody, PPAR-gamma antibody, PPARG antibody, PPARG_HUMAN antibody, PPARG1 antibody, PPARG2 antibody, PPARgamma antibody

UniProt: P37231

Pathways: MAPK Signalweg, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Endopeptidase Activity, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation