FKBP8 Antikörper (AA 58-190)

Produktnummer ABIN7162843

Dieses Anti-FKBP8-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von FKBP8 in WB, ELISA und IHC. Geeignet für Human.

Kurzübersicht für FKBP8 Antikörper (AA 58-190) (ABIN7162843)

Target: FKBP8 (FK506 Binding Protein 8, 38kDa (FKBP8))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FKBP8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-FKBP8 Antikörper

Bindungsspezifität: AA 58-190

Kreuzreaktivität: Human, Maus

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Peptidyl-prolyl cis-trans isomerase FKBP8 protein (58-190AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu FKBP8

Target: FKBP8 (FK506 Binding Protein 8, 38kDa (FKBP8))

Andere Bezeichnung: FKBP8

Hintergrund:

Background: Constitutively inactive PPiase, which becomes active when bound to calmodulin and calcium. Seems to act as a chaperone for BCL2, targets it to the mitochondria and modulates its phosphorylation state. The BCL2/FKBP8/calmodulin/calcium complex probably interferes with the binding of BCL2 to its targets. The active form of FKBP8 may therefore play a role in the regulation of apoptosis.

Aliases: 38 kDa FK506-binding protein antibody, 38 kDa FKBP antibody, 38 kDa antibody, FK506 binding protein 8 antibody, FK506 binding protein 8, 38 kDa antibody, FK506 binding protein, 38 kDa antibody, FK506-binding protein 8 antibody, FKBP 38 antibody, FKBP-38 antibody, FKBP-8 antibody, Fkbp8 antibody, FKBP8_HUMAN antibody, FKBPR38 antibody, hFKBP38 antibody, Peptidyl-prolyl cis-trans isomerase FKBP8 antibody, PPIase FKBP8 antibody, Rotamase antibody, Sam11 antibody

UniProt: Q14318

Pathways: Autophagie