NUMA1 Antikörper (AA 627-870)

Produktnummer ABIN7161807

Der Kaninchen Polyklonal Anti-NUMA1-Antikörper wurde für WB, IHC, ELISA und IF validiert. Er ist geeignet, NUMA1 in Proben von Human zu detektieren.

Kurzübersicht für NUMA1 Antikörper (AA 627-870) (ABIN7161807)

Target: NUMA1 (Nuclear Mitotic Apparatus Protein 1 (NUMA1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NUMA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-NUMA1 Antikörper

Bindungsspezifität: AA 627-870

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Nuclear mitotic apparatus protein 1 protein (627-870AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu NUMA1

Target: NUMA1 (Nuclear Mitotic Apparatus Protein 1 (NUMA1))

Andere Bezeichnung: NUMA1

Hintergrund:

Background: Highly abundant component of the nuclear matrix where it may serve a non-mitotic structural role, occupies the majority if the nuclear volume (PubMed:10075938). Required for maintenance and establishment of the mitotic spindle poles during symmetric cell divisions, functioning as a tether linking bulk microtubules of the spindle to centrosomes (PubMed:7769006, PubMed:11956313, PubMed:26195665). Also required for proper alignment of the mitotic spindle during asymmetric cell divisions (PubMed:21816348).

Aliases: Centrophilin stabilizes mitotic spindle in mitotic cells antibody, NMP 22 antibody, Nuclear matrix protein 22 antibody, Nuclear mitotic apparatus protein 1 antibody, Nuclear mitotic apparatus protein antibody, NUMA 1 antibody, NUMA antibody, NuMA protein antibody, NUMA1 antibody, NUMA1_HUMAN antibody, SP H antigen antibody, SP-H antigen antibody, Structural nuclear protein antibody

UniProt: Q14980

Pathways: Caspase Kaskade in der Apoptose, Regulation of Actin Filament Polymerization, M Phase