NHEJ1 Antikörper (AA 225-296) (Biotin)

Produktnummer ABIN7161683

Produktdetails anti-NHEJ1 Antikörper (Biotin)

Target: NHEJ1 (Nonhomologous End-Joining Factor 1 (NHEJ1))

Bindungsspezifität: AA 225-296

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NHEJ1 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Non-homologous end-joining factor 1 protein (225-296AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu NHEJ1

Target: NHEJ1 (Nonhomologous End-Joining Factor 1 (NHEJ1))

Andere Bezeichnung: NHEJ1 (NHEJ1 Produkte)

Synonyme: NHEJ1 antikoerper, zgc:85657 antikoerper, XLF antikoerper, 1700029B21Rik antikoerper, cernunnos antikoerper, non-homologous end joining factor 1 antikoerper, non-homologous end joining factor 1 S homeolog antikoerper, solute carrier family 23 member 3 antikoerper, nonhomologous end-joining factor 1 antikoerper, NHEJ1 antikoerper, nhej1.S antikoerper, nhej1 antikoerper, SLC23A3 antikoerper, Nhej1 antikoerper

Hintergrund:

Background: DNA repair protein involved in DNA nonhomologous end joining (NHEJ) required for double-strand break (DSB) repair and V(D)J recombination. May serve as a bridge between XRCC4 and the other NHEJ factors located at DNA ends, or may participate in reconfiguration of the end bound NHEJ factors to allow XRCC4 access to the DNA termini. It may act in concert with XRCC6/XRCC5 (Ku) to stimulate XRCC4-mediated joining of blunt ends and several types of mismatched ends that are noncomplementary or partially complementary (PubMed:16439204, PubMed:16439205, PubMed:17470781). Binds DNA in a length-dependent manner (PubMed:17317666).

Aliases: Cernunnos antibody, FLJ12610 antibody, NHEJ 1 antibody, Nhej1 antibody, NHEJ1, S. cerevisiae, homolog of antibody, NHEJ1_HUMAN antibody, Non homologous end joining factor 1 antibody, Non-homologous end-joining factor 1 antibody, Nonhomologous end joining factor 1 antibody, OTTHUMP00000164168 antibody, OTTHUMP00000206275 antibody, OTTHUMP00000206279 antibody, Protein cernunnos antibody, XLF antibody, XRCC4 like factor antibody, XRCC4-like factor antibody

UniProt: Q9H9Q4

Pathways: DNA Reparatur