NMNAT1 Antikörper (AA 1-279)

Produktnummer ABIN7161578

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch NMNAT1 in IHC und ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für NMNAT1 Antikörper (AA 1-279) (ABIN7161578)

Target: NMNAT1 (Nicotinamide Nucleotide Adenylyltransferase 1 (NMNAT1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NMNAT1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA

Produktdetails anti-NMNAT1 Antikörper

Bindungsspezifität: AA 1-279

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 protein (1-279AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu NMNAT1

Target: NMNAT1 (Nicotinamide Nucleotide Adenylyltransferase 1 (NMNAT1))

Andere Bezeichnung: NMNAT1

Hintergrund:

Background: Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form, nicotinic acid mononucleotide (NaMN) as substrate with the same efficiency. Can use triazofurin monophosphate (TrMP) as substrate. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD(+). For the pyrophosphorolytic activity, prefers NAD(+) and NaAD as substrates and degrades NADH, nicotinic acid adenine dinucleotide phosphate (NHD) and nicotinamide guanine dinucleotide (NGD) less effectively. Fails to cleave phosphorylated dinucleotides NADP(+), NADPH and NaADP(+). Protects against axonal degeneration following mechanical or toxic insults.

Aliases: EC 2.7.7.1 antibody, LCA9 antibody, Leber's congenital amaurosis 9 antibody, NaMN adenylyltransferase 1 antibody, nicotinamide nucleotide adenylyltransferase 1 antibody, Nicotinamide-nucleotide adenylyltransferase 1 antibody, Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 antibody, nicotinate nucleotide adenylyltransferase 1 antibody, Nicotinate-nucleotide adenylyltransferase 1 antibody, NMN adenylyltransferase 1 antibody, NMN/NaMN adenylyltransferase 1 antibody, NMNA1_HUMAN antibody, Nmnat 1 antibody, Nmnat1 antibody, OTTHUMP00000001731 antibody, OTTHUMP00000001732 antibody, OTTHUMP00000035892 antibody, PNAT 1 antibody, PNAT1 antibody, pyridine nucleotide adenylyltransferase 1 antibody

UniProt: Q9HAN9