UBA3 Antikörper (Catalytic Subunit)
Kurzübersicht für UBA3 Antikörper (Catalytic Subunit) (ABIN7161136)
Target
Alle UBA3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 234-463, Catalytic Subunit
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Kreuzreaktivität
- Human
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Aufreinigung
- Antigen Affinity Purified
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Immunogen
- Recombinant Human NEDD8-activating enzyme E1 catalytic subunit protein (234-463AA)
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Isotyp
- IgG
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Applikationshinweise
- Recommended dilution: IHC:1:20-1:200,
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- UBA3 (Ubiquitin-Like Modifier Activating Enzyme 3 (UBA3))
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Andere Bezeichnung
- UBA3
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Hintergrund
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Background: Catalytic subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Down-regulates steroid receptor activity. Necessary for cell cycle progression.
Aliases: DKFZp566J164 antibody, EC 6.3.2. antibody, hUba3 antibody, MGC22384 antibody, NEDD8 activating enzyme E1 catalytic subunit antibody, NEDD8 activating enzyme E1C antibody, Nedd8 activating enzyme hUba3 antibody, NEDD8-activating enzyme E1 catalytic subunit antibody, NEDD8-activating enzyme E1C antibody, uba3 antibody, UBA3 ubiquitin activating enzyme E1 homolog antibody, UBA3_HUMAN antibody, UBE1C antibody, Ubiquitin activating enzyme 3 antibody, Ubiquitin activating enzyme E1C antibody, Ubiquitin-activating enzyme 3 antibody, Ubiquitin-activating enzyme E1C antibody, Ubiquitin-like modifier-activating enzyme 3 antibody
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UniProt
- Q8TBC4
Target
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