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NANOS2 Antikörper (AA 1-138)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch NANOS2 in ELISA, IHC und IF. Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN7161035

Kurzübersicht für NANOS2 Antikörper (AA 1-138) (ABIN7161035)

Target

Alle NANOS2 Antikörper anzeigen
NANOS2 (Nanos Homolog 2 (NANOS2))

Reaktivität

  • 32
  • 5
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 29
  • 3
Kaninchen

Klonalität

  • 31
  • 1
Polyklonal

Konjugat

  • 17
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser NANOS2 Antikörper ist unkonjugiert

Applikation

  • 20
  • 16
  • 4
  • 3
  • 2
  • 2
ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • Bindungsspezifität

    • 7
    • 7
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-138

    Kreuzreaktivität

    Human

    Aufreinigung

    >95%, Protein G purified

    Immunogen

    Recombinant Human Nanos homolog 2 protein (1-138AA)

    Isotyp

    IgG
  • Applikationshinweise

    Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C,-80 °C

    Informationen zur Lagerung

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target

    NANOS2 (Nanos Homolog 2 (NANOS2))

    Andere Bezeichnung

    NANOS2

    Hintergrund

    Background: Plays a key role in the sexual differentiation of germ cells by promoting the male fate but suppressing the female fate. Represses the female fate pathways by suppressing meiosis, which in turn results in the promotion of the male fate. Maintains the suppression of meiosis by preventing STRA8 expression, which is required for premeiotic DNA replication, after CYP26B1 is decreased. Regulates the localization of the CCR4-NOT deadenylation complex to P-bodies and plays a role in recruiting the complex to trigger the degradation of mRNAs involved in meiosis. Required for the maintenance of the spermatogonial stem cell population. Not essential for the assembly of P-bodies but is required for the maintenance of their normal state.

    Aliases: NANO2_HUMAN antibody, Nanos homolog 2 antibody, Nanos homolog 2 Drosophila antibody, NANOS2 antibody, NOS-2 antibody, NOS2 antibody

    UniProt

    P60321

    Pathways

    Retinoic Acid Receptor Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Stem Cell Maintenance
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