NANOS2 Antikörper (C-Term)

Produktnummer ABIN6990923

Der Kaninchen Polyklonal anti-NANOS2 Antikörper wird verwendet zum Nachweis von NANOS2 in Proben von Human, Maus und Ratte. Er wurde validiert für ELISA und WB.

Kurzübersicht für NANOS2 Antikörper (C-Term) (ABIN6990923)

Target: NANOS2 (Nanos Homolog 2 (NANOS2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NANOS2 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Produktdetails anti-NANOS2 Antikörper

Bindungsspezifität: C-Term

Spezifität: This Nanos2 antibody will not cross-react with either Nanos 1 or Nanos3.

Aufreinigung: Nanos2 Antibody is affinity chromatography purified via peptide column.

Immunogen: Nanos2 antibody was raised against a 13 amino acid synthetic peptide near the carboxy terminus of the human Nanos2. The immunogen is located within the last 50 amino acids of Nanos2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Nanos2 antibody can be used for detection of Nanos2 by Western blot at 2 to 4 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Nanos2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: Nanos2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu NANOS2

Target: NANOS2 (Nanos Homolog 2 (NANOS2))

Andere Bezeichnung: Nanos2

Hintergrund: Nanos2 Antibody: Nanos is a zinc-finger containing, RNA-binding protein that has been implicated in germ cell development in both invertebrates and vertebrates. In drosophila, Nanos represses apoptosis during development to ensure proper germ-line development. Unlike Nanos1 whose expression in mice is dispensable, the Nanos2 and Nanos3 proteins are required for germ cell development. Nanos2-null primordial germ cells (PGCs) die only in the male gonads and show no defects in females, while Nanos3-null PGCs are lost during the migration stage regardless of sex. Nanos2 and Nanos3 have distinct expression patterns during embryo development, suggesting that these two proteins do not have redundant functions. However, expression of Nanos2 can at least partially replace Nanos3 function in a Nanos3-null background. Nanos3 expression can not rescue Nanos2-null defects.

Gen-ID: 339345

UniProt: P60321

Pathways: Retinoic Acid Receptor Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Stem Cell Maintenance