FAT Atypical Cadherin 2 (FAT2) (AA 123-314) Antikörper (Biotin)

Produktnummer ABIN7160332

Dieses Anti--Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von in ELISA. Geeignet für Human.

Kurzübersicht für FAT Atypical Cadherin 2 (FAT2) (AA 123-314) Antikörper (Biotin) (ABIN7160332)

Target: FAT Atypical Cadherin 2 (FAT2)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Biotin

Applikation: ELISA

Produktdetails

Bindungsspezifität: AA 123-314

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Multiple epidermal growth factor-like domains protein 10 protein (123-314AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Antigendetails

Target: FAT Atypical Cadherin 2 (FAT2)

Andere Bezeichnung: MEGF1

Hintergrund:

Background: Membrane receptor involved in phagocytosis by macrophages of apoptotic cells. Cooperates with ABCA1 within the process of engulfment. Promotes the formation of large intracellular vacuoles and may be responsible for the uptake of amyloid-beta peptides. May also function in the mosaic spacing of specific neuron subtypes in the retina through homotypic retinal neuron repulsion. Mosaics provide a mechanism to distribute each cell type evenly across the retina, ensuring that all parts of the visual field have access to a full set of processing elements. May play role in cell adhesion and motility. Is also an essential factor in the regulation of myogenesis. Controls the balance between skeletal muscle satellite cells proliferation and differentiation problably through regulation of the notch signaling pathway.

Aliases: MEGF10 antibody, KIAA1780Multiple epidermal growth factor-like domains protein 10 antibody, Multiple EGF-like domains protein 10 antibody

UniProt: Q96KG7