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SMAD2 Antikörper (AA 2-467)

Name: SMAD2 Antikörper (AA 2-467)
Brand: antibodies-online
SKU: ABIN7160228
Price: 394.68 EUR
Availability: InStock

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch SMAD2 in WB, ELISA, IHC und IF. Er zeigt eine Reaktivität gegenüber Human.

Western Blot Positive WB detected in: Hela whole cell lysate, HepG2 whole cell lysate, Jurkat whole cell lysate, K562 whole cell lysate, Mouse heart tissue, Mouse liver tissue, Mouse brain tissue All lanes: SMAD2 antibody at 3 μg/mL Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 53, 49 kDa Observed band size: 53 kDa (SMAD2 Antikörper (AA 2-467))

IHC image of ABIN7160228 diluted at 1:600 and staining in paraffin-embedded human prostate tissue performed on a Leica BondTM system. (SMAD2 Antikörper (AA 2-467))

IHC

Immunohistochemistry of paraffin-embedded human testis tissue using ABIN7160228 at dilution of 1:100 (SMAD2 Antikörper (AA 2-467))

IHC

Immunofluorescent analysis of HepG2 cells using ABIN7160228 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L) (SMAD2 Antikörper (AA 2-467))

Western Blot Positive WB detected in: MCF-7 whole cell lysate All lanes: SMAD2 antibody at 3 μg/mL Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 53, 49 kDa Observed band size: 53 kDa (SMAD2 Antikörper (AA 2-467))

Immunofluorescence staining of Hela cells with ABIN7160228 at 1:200, counter-stained with DAPI. (SMAD2 Antikörper (AA 2-467))

6 Abbildungen

Produktnummer ABIN7160228

Kurzübersicht für SMAD2 Antikörper (AA 2-467) (ABIN7160228)

Target

Alle SMAD2 Antikörper anzeigen

SMAD2 (SMAD, Mothers Against DPP Homolog 2 (SMAD2))

Reaktivität

Human

Wirt

Kaninchen

Klonalität

Polyklonal

Konjugat

Dieser SMAD2 Antikörper ist unkonjugiert

Applikation

Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Discover our top product SMAD2 Primärantikörper

Bindungsspezifität
56

44

29

28

24

22

9

9

8

7

6

6

5

4

4

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 2-467

Kreuzreaktivität

Human, Maus

Aufreinigung

>95%, Protein G purified

Immunogen

Recombinant Human Mothers against decapentaplegic homolog 2 protein (2-467AA)

Isotyp

IgG
anti-SMAD, Mothers Against DPP Homolog 2 (SMAD2) (AA 181-280) antibody
SMAD2 Reaktivität: Human WB, ELISA, IF, IHC (p) Wirt: Maus Monoclonal 3G9 unconjugated

anti-SMAD, Mothers Against DPP Homolog 2 (SMAD2) (pSer423), (pSer425), (pSer465), (pSer467) antibody
SMAD2 Reaktivität: Human, Maus, Ratte WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated

anti-SMAD, Mothers Against DPP Homolog 2 (SMAD2) (C-Term) antibody
SMAD2 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-SMAD, Mothers Against DPP Homolog 2 (SMAD2) (AA 181-280) antibody
SMAD2 Reaktivität: Human WB, ELISA, IF, IHC (p) Wirt: Maus Monoclonal 4D10 unconjugated

anti-SMAD, Mothers Against DPP Homolog 2 (SMAD2) (pSer467) antibody
SMAD2 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-SMAD, Mothers Against DPP Homolog 2 (SMAD2) (N-Term) antibody
SMAD2 Reaktivität: Human, Maus, Ratte WB, IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated

anti-SMAD, Mothers Against DPP Homolog 2 (SMAD2) (pThr183), (pThr221) antibody
SMAD2 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated

anti-SMAD, Mothers Against DPP Homolog 2 (SMAD2) (AA 181-280) antibody
SMAD2 Reaktivität: Human WB, ELISA, PLA Wirt: Maus Monoclonal 2D7 unconjugated

anti-SMAD, Mothers Against DPP Homolog 2 (SMAD2) (AA 27-172) antibody
SMAD2 Reaktivität: Human, Maus, Ratte WB, IHC, IF, IP Wirt: Maus Monoclonal 48-MAD2 unconjugated

anti-SMAD, Mothers Against DPP Homolog 2 (SMAD2) (AA 94-112), (N-Term) antibody
SMAD2 Reaktivität: Human WB, IHC, ICC Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

Recommended dilution: WB:1:500-1:5000, IHC:1:100-1:1000, IF:1:50-1:500,

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel

ProClin

Vorsichtsmaßnahmen

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

-20 °C,-80 °C

Informationen zur Lagerung

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target

SMAD2 (SMAD, Mothers Against DPP Homolog 2 (SMAD2))

Andere Bezeichnung

SMAD2

Hintergrund

Background: Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.
Aliases: Drosophila, homolog of, MADR2 antibody, hMAD-2 antibody, HsMAD2 antibody, JV18 antibody, JV18-1 antibody, JV181 antibody, MAD antibody, MAD homolog 2 antibody, MAD Related Protein 2 antibody, Mad-related protein 2 antibody, MADH2 antibody, MADR2 antibody, MGC22139 antibody, MGC34440 antibody, Mother against DPP homolog 2 antibody, Mothers against decapentaplegic homolog 2 antibody, Mothers against decapentaplegic, Drosophila, homolog of, 2 antibody, Mothers against DPP homolog 2 antibody, OTTHUMP00000163489 antibody, Sma and Mad related protein 2 antibody, Sma- and Mad-related protein 2 MAD antibody, SMAD 2 antibody, SMAD family member 2 antibody, SMAD, mothers against DPP homolog 2 antibody, SMAD2 antibody, SMAD2_HUMAN antibody

UniProt

Q15796

Pathways

Zellzyklus, Hormone Transport, Chromatin Binding, Protein targeting to Nucleus