SMCR7L Antikörper (AA 51-309) (HRP)

Produktnummer ABIN7159856

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch SMCR7L in ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für SMCR7L Antikörper (AA 51-309) (HRP) (ABIN7159856)

Target: SMCR7L (Smith-Magenis Syndrome Chromosome Region, Candidate 7-Like (SMCR7L))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SMCR7L Antikörper ist konjugiert mit HRP

Applikation: ELISA

Produktdetails anti-SMCR7L Antikörper (HRP)

Bindungsspezifität: AA 51-309

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Mitochondrial dynamics protein MID51 protein (51-309AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu SMCR7L

Target: SMCR7L (Smith-Magenis Syndrome Chromosome Region, Candidate 7-Like (SMCR7L))

Andere Bezeichnung: MIEF1

Hintergrund:

Background: Mitochondrial outer membrane protein which regulates mitochondrial fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface independently of the mitochondrial fission FIS1 and MFF proteins. Regulates DNM1L GTPase activity and DNM1L oligomerization. Binds ADP and can also bind GDP, although with lower affinity. Does not bind CDP, UDP, ATP, AMP or GTP. Inhibits DNM1L GTPase activity in the absence of bound ADP. Requires ADP to stimulate DNM1L GTPase activity and the assembly of DNM1L into long, oligomeric tubules with a spiral pattern, as opposed to the ring-like DNM1L oligomers observed in the absence of bound ADP. Does not require ADP for its function in recruiting DNM1L.

Aliases: MIEF1 antibody, MID51 antibody, SMCR7L antibody, Mitochondrial dynamics protein MID51 antibody, Mitochondrial dynamics protein of 51 kDa antibody, Mitochondrial elongation factor 1 antibody, Smith-Magenis syndrome chromosomal region candidate gene 7 protein-like antibody, SMCR7-like protein antibody

UniProt: Q9NQG6