MBTPS1 Antikörper (AA 803-1052)
Kurzübersicht für MBTPS1 Antikörper (AA 803-1052) (ABIN7159380)
Target
Alle MBTPS1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 803-1052
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Kreuzreaktivität
- Human
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Aufreinigung
- Antigen Affinity Purified
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Immunogen
- Recombinant Human Membrane-bound transcription factor site-1 protease protein (803-1052AA)
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Isotyp
- IgG
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Applikationshinweise
- Recommended dilution: IHC:1:20-1:200,
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- MBTPS1 (Membrane-Bound Transcription Factor Peptidase, Site 1 (MBTPS1))
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Andere Bezeichnung
- MBTPS1
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Hintergrund
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Background: Serine protease that catalyzes the first step in the proteolytic activation of the sterol regulatory element-binding proteins (SREBPs). Other known substrates are BDNF, GNPTAB and ATF6. Cleaves after hydrophobic or small residues, provided that Arg or Lys is in position P4. Cleaves known substrates after Arg-Ser-Val-Leu (SERBP-2), Arg-His-Leu-Leu (ATF6), Arg-Gly-Leu-Thr (BDNF) and its own propeptide after Arg-Arg-Leu-Leu. Mediates the protein cleavage of GNPTAB into subunit alpha and beta, thereby participating in biogenesis of lysosomes.
Aliases: MBTPS1 antibody, KIAA0091 antibody, S1P antibody, SKI1Membrane-bound transcription factor site-1 protease antibody, EC 3.4.21.112 antibody, Endopeptidase S1P antibody, Subtilisin/kexin-isozyme 1 antibody, SKI-1 antibody
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UniProt
- Q14703
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Pathways
- ER-Nucleus Signaling
Target
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