KDM4A Antikörper (AA 127-364)

Produktnummer ABIN7158695

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch KDM4A in IHC, ELISA und IF. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für KDM4A Antikörper (AA 127-364) (ABIN7158695)

Target: KDM4A (Lysine (K)-Specific Demethylase 4A (KDM4A))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KDM4A Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-KDM4A Antikörper

Bindungsspezifität: AA 127-364

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Lysine-specific demethylase 4A protein (127-364AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu KDM4A

Target: KDM4A (Lysine (K)-Specific Demethylase 4A (KDM4A))

Andere Bezeichnung: KDM4A

Hintergrund:

Background: Histone demethylase that specifically demethylates \'Lys-9\' and \'Lys-36\' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 \'Lys-4\', H3 \'Lys-27\' nor H4 \'Lys-20\'. Demethylates trimethylated H3 \'Lys-9\' and H3 \'Lys-36\' residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate. Participates in transcriptional repression of ASCL2 and E2F-responsive promoters via the recruitment of histone deacetylases and NCOR1, respectively.

Aliases: JHDM3A antibody, JmjC domain containing histone demethylation protein 3A antibody, JmjC domain-containing histone demethylation protein 3A antibody, JMJD2 antibody, JMJD2A antibody, jumonji C domain containing histone demethylase 3A antibody, Jumonji domain containing 2 antibody, Jumonji domain containing 2A antibody, Jumonji domain containing protein 2A antibody, Jumonji domain-containing protein 2A antibody, KDM4A antibody, KDM4A_HUMAN antibody, KIAA0677 antibody, Lysine (K) specific demethylase 4A antibody, Lysine-specific demethylase 4A antibody, TDRD14A antibody, Tudor domain containing 14A antibody

UniProt: O75164

Pathways: Warburg Effekt