CD47 Antikörper (AA 44-141)

Produktnummer ABIN7158282

Der Kaninchen Polyklonal Anti-CD47-Antikörper wurde für IF, IHC und ELISA validiert. Er ist geeignet, CD47 in Proben von Human zu detektieren.

Kurzübersicht für CD47 Antikörper (AA 44-141) (ABIN7158282)

Target: CD47

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD47 Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF), Immunohistochemistry (IHC), ELISA

Produktdetails anti-CD47 Antikörper

Bindungsspezifität: AA 44-141

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Leukocyte surface antigen CD47 protein (44-141AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu CD47

Target: CD47

Andere Bezeichnung: CD47

Hintergrund:

Background: Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus (By similarity). Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integrin dependent signal transduction. May prevent premature elimination of red blood cells. May be involved in membrane permeability changes induced following virus infection.

Aliases: Antigen identified by monoclonal antibody 1D8 antibody, Antigenic surface determinant protein OA3 antibody, CD 47 antibody, CD47 antibody, CD47 antigen (Rh-related antigen, integrin-associated signal transducer) antibody, CD47 antigen antibody, CD47 glycoprotein antibody, CD47 Molecule antibody, CD47_HUMAN antibody, IAP antibody, Integrin Associated Protein antibody, Integrin associated signal transducer antibody, Integrin-associated protein antibody, Leukocyte surface antigen CD47 antibody, MER 6 antibody, MER6 antibody, OA 3 antibody, OA3 antibody, OTTHUMP00000041152 antibody, OTTHUMP00000041153 antibody, Protein MER6 antibody, Rh related antigen antibody, Surface antigen identified by monoclonal antibody 1D8 antibody

UniProt: Q08722