LRPPRC Antikörper (AA 901-1036)

Produktnummer ABIN7158045

Der Kaninchen Polyklonal Anti-LRPPRC-Antikörper wurde für WB, IHC, ELISA, IF und IP validiert. Er ist geeignet, LRPPRC in Proben von Human zu detektieren.

Kurzübersicht für LRPPRC Antikörper (AA 901-1036) (ABIN7158045)

Target: LRPPRC (Leucine-Rich PPR-Motif Containing (LRPPRC))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LRPPRC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)

Produktdetails anti-LRPPRC Antikörper

Bindungsspezifität: AA 901-1036

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Leucine-rich PPR motif-containing protein, mitochondrial protein (901-1036AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500, IF:1:50-1:200, IP:1:200-1:2000,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu LRPPRC

Target: LRPPRC (Leucine-Rich PPR-Motif Containing (LRPPRC))

Andere Bezeichnung: LRPPRC

Hintergrund:

Background: May play a role in RNA metabolism in both nuclei and mitochondria. In the nucleus binds to HNRPA1-associated poly(A) mRNAs and is part of nmRNP complexes at late stages of mRNA maturation which are possibly associated with nuclear mRNA export. May bind mature mRNA in the nucleus outer membrane. In mitochondria binds to poly(A) mRNA. Plays a role in translation or stability of mitochondrially encoded cytochrome c oxidase (COX) subunits. May be involved in transcription regulation. Cooperates with PPARGC1A to regulate certain mitochondrially encoded genes and gluconeogenic genes and may regulate docking of PPARGC1A to transcription factors. Seems to be involved in the transcription regulation of the multidrug-related genes MDR1 and MVP. Part of a nuclear factor that binds to the invMED1 element of MDR1 and MVP gene promoters. Binds single-stranded DNA (By similarity).

Aliases: 130 kDa leucine-rich protein antibody, gp130 antibody, Leucine-rich PPR motif-containing protein antibody, Leucine-rich PPR-motif containing protein antibody, LPPRC_HUMAN antibody, LRP 130 antibody, lrpprc antibody, mitochondrial antibody

UniProt: P42704