LGMN Antikörper (AA 199-312) (HRP)

Produktnummer ABIN7157974

Dieses Anti-LGMN-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von LGMN in ELISA. Geeignet für Human.

Kurzübersicht für LGMN Antikörper (AA 199-312) (HRP) (ABIN7157974)

Target: LGMN (Legumain (LGMN))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LGMN Antikörper ist konjugiert mit HRP

Applikation: ELISA

Produktdetails anti-LGMN Antikörper (HRP)

Bindungsspezifität: AA 199-312

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Legumain protein (199-312AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu LGMN

Target: LGMN (Legumain (LGMN))

Andere Bezeichnung: LGMN

Hintergrund:

Background: Has a strict specificity for hydrolysis of asparaginyl bonds. Can also cleave aspartyl bonds slowly, especially under acidic conditions. Required for normal lysosomal protein degradation in renal proximal tubules. Required for normal degradation of internalized EGFR. Plays a role in the regulation of cell proliferation via its role in EGFR degradation (By similarity). May be involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system.

Aliases: AEP antibody, Asparaginyl endopeptidase antibody, cysteine 1 antibody, Cysteine protease 1 antibody, EC 3.4.22.34 antibody, Legumain antibody, LGMN antibody, LGMN_HUMAN antibody, LGMN1 antibody, Protease antibody, Protease cysteine 1 (legumain) antibody, Protease cysteine 1 antibody, PRSC1 antibody

UniProt: Q99538

Pathways: Metabolism of Steroid Hormones and Vitamin D, Activation of Innate immune Response, Toll-Like Receptors Cascades