KANK2 Antikörper (AA 410-585)

Produktnummer ABIN7157690

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch KANK2 in ELISA und IHC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für KANK2 Antikörper (AA 410-585) (ABIN7157690)

Target: KANK2 (KN Motif and Ankyrin Repeat Domains 2 (KANK2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KANK2 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktdetails anti-KANK2 Antikörper

Bindungsspezifität: AA 410-585

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human KN motif and ankyrin repeat domain-containing protein 2 protein (410-585AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:200-1:500,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu KANK2

Target: KANK2 (KN Motif and Ankyrin Repeat Domains 2 (KANK2))

Andere Bezeichnung: KANK2

Hintergrund:

Background: Involved in transcription regulation by sequestering nuclear receptor coactivators, such as NCOA1, NCOA2 and NCOA3, in the cytoplasm, the function is deregulated by phosphorylation. Involved in the negative control of vitamin D receptor signaling pathway (PubMed:24671081). May be involved in the control of cytoskeleton formation by regulating actin polymerization. Involved in regulation of caspase-independent apoptosis, proposed to sequester AIFM1 in mitochondria and apoptotic stimuli lead to its proteasomal degradation allowing the release of AIFM1 to the nucleus (PubMed:22371500). May be involved in promotion of cell proliferation (By similarity).

Aliases: KANK2 antibody, ANKRD25 antibody, KIAA1518 antibody, MXRA3 antibody, SIP antibody, KN motif and ankyrin repeat domain-containing protein 2 antibody, Ankyrin repeat domain-containing protein 25 antibody, Matrix-remodeling-associated protein 3 antibody, SRC-1-interacting protein antibody, SIP antibody, SRC-interacting protein antibody, SRC1-interacting protein antibody

UniProt: Q63ZY3