IL-4 Antikörper (AA 25-153)

Produktnummer ABIN7156913

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch IL-4 in ELISA und IHC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für IL-4 Antikörper (AA 25-153) (ABIN7156913)

Target: IL-4 (IL4) (Interleukin 4 (IL4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL-4 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktdetails anti-IL-4 Antikörper

Bindungsspezifität: AA 25-153

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Interleukin-4 protein (25-153AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:200-1:500,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu IL-4

Target: IL-4 (IL4) (Interleukin 4 (IL4))

Andere Bezeichnung: IL4

Hintergrund:

Background: Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Genetic variations in IL4 may be a cause of susceptibility to ischemic stroke (ISCHSTR) [MIM:601367], also known as cerebrovascular accident or cerebral infarction. A stroke is an acute neurologic event leading to death of neural tissue of the brain and resulting in loss of motor, sensory and/or cognitive function. Ischemic strokes, resulting from vascular occlusion, is considered to be a highly complex disease consisting of a group of heterogeneous disorders with multiple genetic and environmental risk factors.

Aliases: B cell growth factor 1 antibody, B cell IgG differentiation factor antibody, B Cell Stimulatory Factor 1 antibody, B-cell stimulatory factor 1 antibody, BCGF 1 antibody, BCGF1 antibody, Binetrakin antibody, BSF-1 antibody, BSF1 antibody, IGG1 induction factor antibody, IL 4 antibody, IL-4 antibody, IL4 antibody, IL4_HUMAN antibody, Il4e12 antibody, Interleukin 4 antibody, Interleukin 4 variant 2 antibody, Interleukin 4, isoform 1 antibody, Interleukin-4 antibody, Lymphocyte stimulatory factor 1 antibody, MGC79402 antibody, Pitrakinra antibody

UniProt: P05112

Pathways: JAK-STAT Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport, Activated T Cell Proliferation