IRF4 Antikörper (AA 180-451)

Produktnummer ABIN7156622

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch IRF4 in ELISA und IHC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für IRF4 Antikörper (AA 180-451) (ABIN7156622)

Target: IRF4 (Interferon Regulatory Factor 4 (IRF4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IRF4 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktdetails anti-IRF4 Antikörper

Bindungsspezifität: AA 180-451

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Interferon regulatory factor 4 protein (180-451AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu IRF4

Target: IRF4 (Interferon Regulatory Factor 4 (IRF4))

Andere Bezeichnung: IRF4

Hintergrund:

Background: Transcriptional activator. Binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. Involved in CD8+ dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5\\\'-TGAnTCA/GAAA-3\\\'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF4 and activation of genes.

Aliases: Interferon regulatory factor 4 antibody, IRF 4 antibody, IRF-4 antibody, Irf4 antibody, IRF4_HUMAN antibody, LSIRF antibody, Lymphocyte specific interferon regulatory factor antibody, Lymphocyte specific IRF antibody, Lymphocyte-specific interferon regulatory factor antibody, Multiple myeloma oncogene 1 antibody, MUM 1 antibody, MUM1 antibody, NF EM5 antibody, NF-EM5 antibody, NFEM5 antibody, PU.1 interaction partner antibody, Sfpi1/PU.1 interaction partner antibody, Transcriptional activator PIP antibody

UniProt: Q15306

Pathways: Chromatin Binding