Integrin beta 4 Antikörper (AA 1401-1533)
Kurzübersicht für Integrin beta 4 Antikörper (AA 1401-1533) (ABIN7156486)
Target
Alle Integrin beta 4 (ITGB4) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1401-1533
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Kreuzreaktivität
- Human, Maus
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Aufreinigung
- >95%, Protein G purified
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Immunogen
- Recombinant Human Integrin beta-4 protein (1401-1533AA)
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Isotyp
- IgG
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Applikationshinweise
- Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Integrin beta 4 (ITGB4)
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Andere Bezeichnung
- ITGB4
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Hintergrund
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Background: Integrin alpha-6/beta-4 is a receptor for laminin. Plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility. ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling (PubMed:20682778). ITGA6:ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling (PubMed:22351760).
Aliases: CD 104 antibody, CD104 antibody, CD104 antigen antibody, gp150 antibody, Integrin beta 4 subunit antibody, Integrin beta-4 antibody, ITB4_HUMAN antibody, ITG B4 antibody, ITGB 4 antibody, Itgb4 antibody
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UniProt
- P16144
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Pathways
- Integrin Complex
Target
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