FKBP6 Antikörper (AA 101-327)

Produktnummer ABIN7156155

Der Kaninchen Polyklonal Anti-FKBP6-Antikörper wurde für WB, ELISA, IHC und IF validiert. Er ist geeignet, FKBP6 in Proben von Human zu detektieren.

Kurzübersicht für FKBP6 Antikörper (AA 101-327) (ABIN7156155)

Target: FKBP6 (FK506 Binding Protein 6, 36kDa (FKBP6))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FKBP6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-FKBP6 Antikörper

Bindungsspezifität: AA 101-327

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Inactive peptidyl-prolyl cis-trans isomerase FKBP6 protein (101-327AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu FKBP6

Target: FKBP6 (FK506 Binding Protein 6, 36kDa (FKBP6))

Andere Bezeichnung: FKBP6

Hintergrund:

Background: Co-chaperone required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Acts as a co-chaperone via its interaction with HSP90 and is required for the piRNA amplification process, the secondary piRNA biogenesis. May be required together with HSP90 in removal of 16 nucleotide ping-pong by-products from Piwi complexes, possibly facilitating turnover of Piwi complexes.

Aliases: 36 kDa FK506 binding protein antibody, 36 kDa FK506-binding protein antibody, 36 kDa FKBP antibody, EC 5.2.1.8 antibody, FK506 binding protein 6 antibody, FK506-binding protein 6 antibody, FKBP 36 antibody, FKBP-36 antibody, FKBP-6 antibody, FKBP36 antibody, fkbp6 antibody, FKBP6_HUMAN antibody, Immunophilin FKBP36 antibody, Peptidyl prolyl cis trans isomerase antibody, Peptidyl-prolyl cis-trans isomerase FKBP6 antibody, PPIase antibody, PPIase FKBP6 antibody, Rotamase antibody

UniProt: O75344

Pathways: M Phase