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Nanog Antikörper (AA 1-305)

NANOG Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7155812
  • Target Alle Nanog (NANOG) Antikörper anzeigen
    Nanog (NANOG) (Nanog Homeobox (NANOG))
    Bindungsspezifität
    • 15
    • 15
    • 9
    • 8
    • 7
    • 7
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-305
    Reaktivität
    • 126
    • 54
    • 21
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 116
    • 19
    • 3
    Kaninchen
    Klonalität
    • 106
    • 32
    Polyklonal
    Konjugat
    • 74
    • 9
    • 7
    • 7
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser Nanog Antikörper ist unkonjugiert
    Applikation
    • 100
    • 60
    • 47
    • 39
    • 25
    • 24
    • 24
    • 18
    • 15
    • 12
    • 9
    • 8
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Kreuzreaktivität
    Human
    Aufreinigung
    >95%, Protein G purified
    Immunogen
    Recombinant Human Homeobox protein NANOG protein (1-305AA)
    Isotyp
    IgG
    Top Product
    Discover our top product NANOG Primärantikörper
  • Applikationshinweise
    Recommended dilution: WB:1:2000-1:5000, IHC:1:20-1:200,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    Nanog (NANOG) (Nanog Homeobox (NANOG))
    Andere Bezeichnung
    NANOG (NANOG Produkte)
    Hintergrund

    Background: Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes. Acts as a transcriptional activator or repressor. Binds optimally to the DNA consensus sequence 5\\\'-TAAT[GT][GT]-3\\\' or 5\\\'-[CG][GA][CG]C[GC]ATTAN[GC]-3\\\'. Able to autorepress its expression in differentiating (ES) cells: binds to its own promoter following interaction with ZNF281/ZFP281, leading to recruitment of the NuRD complex and subsequent repression of expression. When overexpressed, promotes cells to enter into S phase and proliferation.

    Aliases: Embryonic stem cell specific homeobox protein (Nanog) antibody, ENK antibody, FLJ12581 antibody, hNanog antibody, Homeobox protein NANOG antibody, Homeobox transcription factor Nanog antibody, homeobox transcription factor Nanog-delta 48 antibody, NANOG antibody, Nanog homeobox antibody, NANOG_HUMAN antibody

    UniProt
    Q9H9S0
    Pathways
    Stem Cell Maintenance
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