SETD7 Antikörper (AA 1-218) (Biotin)

Produktnummer ABIN7155518

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch SETD7 in ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für SETD7 Antikörper (AA 1-218) (Biotin) (ABIN7155518)

Target: SETD7 (SET Domain Containing (Lysine Methyltransferase) 7 (SETD7))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SETD7 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Produktdetails anti-SETD7 Antikörper (Biotin)

Bindungsspezifität: AA 1-218

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Histone-lysine N-methyltransferase SETD7 protein (1-218AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu SETD7

Target: SETD7 (SET Domain Containing (Lysine Methyltransferase) 7 (SETD7))

Andere Bezeichnung: SETD7

Hintergrund:

Background: Histone methyltransferase that specifically monomethylates \\\'Lys-4\\\' of histone H3. H3 \\\'Lys-4\\\' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes such as collagenase or insulin. Recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription. Has also methyltransferase activity toward non-histone proteins such as p53/TP53, TAF10, and possibly TAF7 by recognizing and binding the [KR]-[STA]-K in substrate proteins. Monomethylates \\\'Lys-189\\\' of TAF10, leading to increase the affinity of TAF10 for RNA polymerase II. Monomethylates \\\'Lys-372\\\' of p53/TP53, stabilizing p53/TP53 and increasing p53/TP53-mediated transcriptional activation.

Aliases: FLJ21193 antibody, H3 K4 HMTase antibody, H3-K4-HMTase SETD7 antibody, H4 lysine 4 specific antibody, Histone H3 K4 methyltransferase antibody, Histone H3 lysine 4 specific methyltransferase antibody, Histone H3-K4 methyltransferase SETD7 antibody, Histone H4 K4 methyltransferase antibody, Histone lysine N methyltransferase antibody, Histone lysine N methyltransferase H3 lysine 4 specific SET7 antibody, Histone-lysine N-methyltransferase SETD7 antibody, KIAA1717 antibody, KMT7 antibody, Lysine methyltransferase antibody, Lysine N-methyltransferase 7 antibody, OTTHUMP00000164543 antibody, OTTHUMP00000220049 antibody, SET 7 antibody, SET 7/9 antibody, SET 9 antibody, SET D7 antibody, SET domain containing (lysine methyltransferase) 7 antibody, SET domain containing protein 7 antibody, SET domain containing protein 8 antibody, SET domain-containing protein 7 antibody, SET7 antibody, SET7/9 antibody, SET9 antibody, Setd7 antibody, SETD7_HUMAN antibody

UniProt: Q8WTS6