SUV420H2/KMT5C Antikörper (AA 235-345)

Produktnummer ABIN7155485

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch SUV420H2/KMT5C in WB, ELISA und IF. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für SUV420H2/KMT5C Antikörper (AA 235-345) (ABIN7155485)

Target: SUV420H2/KMT5C (SUV420H2) (Suppressor of Variegation 4-20 Homolog 2 (SUV420H2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SUV420H2/KMT5C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Produktdetails anti-SUV420H2/KMT5C Antikörper

Bindungsspezifität: AA 235-345

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Histone-lysine N-methyltransferase KMT5C protein (235-345aa)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:1000-1:5000, IF:1:100-1:500,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu SUV420H2/KMT5C

Target: SUV420H2/KMT5C (SUV420H2) (Suppressor of Variegation 4-20 Homolog 2 (SUV420H2))

Andere Bezeichnung: KMT5C

Hintergrund:

Background: Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. KMT5C is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2) (By similarity).

Aliases: Histone-lysine N-methyltransferase KMT5C (EC 2.1.1.43) (Lysine N-methyltransferase 5C) (Lysine-specific methyltransferase 5C) (Suppressor of variegation 4-20 homolog 2) (Su(var)4-20 homolog 2) (Suv4-20h2), KMT5C, SUV420H2

UniProt: Q86Y97