SUV420H2/KMT5C Antikörper (AA 187-214)

Produktnummer ABIN390405

Produktdetails anti-SUV420H2/KMT5C Antikörper

Target: SUV420H2/KMT5C (SUV420H2) (Suppressor of Variegation 4-20 Homolog 2 (SUV420H2))

Bindungsspezifität: AA 187-214

Reaktivität: Maus, Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SUV420H2/KMT5C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Homologie: Rat

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This SUV4-20H2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 187-214 amino acids of human SUV4-20H2.

Klon: RB19392

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-SUV420H2/KMT5C Antikörper (ABIN390405)

Boonsanay, Zhang, Georgieva, Kostin, Qi, Yuan, Zhou, Braun: "Regulation of Skeletal Muscle Stem Cell Quiescence by Suv4-20h1-Dependent Facultative Heterochromatin Formation." in: Cell stem cell, Vol. 18, Issue 2, pp. 229-42, (2016) (PubMed).

Details zu SUV420H2/KMT5C

Target: SUV420H2/KMT5C (SUV420H2) (Suppressor of Variegation 4-20 Homolog 2 (SUV420H2))

Andere Bezeichnung: SUV4-20H2 (SUV420H2 Produkte)

Synonyme: zgc:162876 antikoerper, KMT5C antikoerper, BC024816 antikoerper, Suv4-20h2 antikoerper, lysine methyltransferase 5C antikoerper, suppressor of variegation 4-20 homolog 2 (Drosophila) antikoerper, lysine (K)-specific methyltransferase 5C L homeolog antikoerper, KMT5C antikoerper, kmt5c antikoerper, SUV420H2 antikoerper, kmt5c.L antikoerper, Kmt5c antikoerper

Hintergrund: SUV420H2 is a histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. The protein mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. SUV420H1 is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2).

Molekulargewicht: 52113

Gen-ID: 84787

NCBI Accession: NP_116090

UniProt: Q86Y97