EZH1 Antikörper (AA 160-280)
Kurzübersicht für EZH1 Antikörper (AA 160-280) (ABIN7155475)
Target
Alle EZH1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 160-280
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Kreuzreaktivität
- Human, Maus
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Aufreinigung
- Antigen Affinity Purified
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Immunogen
- Recombinant Human Histone-lysine N-methyltransferase EZH1 protein (160-280AA)
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Isotyp
- IgG
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Applikationshinweise
- Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- EZH1 (Enhancer of Zeste Homolog 1 (EZH1))
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Andere Bezeichnung
- EZH1
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Hintergrund
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Background: Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH1 complex, which methylates \\\'Lys-27\\\' of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate \\\'Lys-27\\\' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Required for embryonic stem cell derivation and self-renewal, suggesting that it is involved in safeguarding embryonic stem cell identity. Compared to EZH2-containing complexes, it is less abundant in embryonic stem cells, has weak methyltransferase activity and plays a less critical role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation.
Aliases: Enhancer of zeste homolog 1 (Drosophila) antibody, Enhancer of zeste homolog 1 antibody, ENX-2 antibody, ENX2 antibody, Ezh1 antibody, EZH1_HUMAN antibody, Histone-lysine N-methyltransferase EZH1 antibody
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UniProt
- Q92800
Target
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