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H2AFX Antikörper (AA 1-143)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch H2AFX in IHC und ELISA. Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN7155386

Kurzübersicht für H2AFX Antikörper (AA 1-143) (ABIN7155386)

Target

Alle H2AFX Antikörper anzeigen
H2AFX (H2A Histone Family, Member X (H2AFX))

Reaktivität

  • 178
  • 91
  • 61
  • 25
  • 25
  • 19
  • 17
  • 11
  • 8
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Human

Wirt

  • 155
  • 26
  • 2
Kaninchen

Klonalität

  • 126
  • 57
Polyklonal

Konjugat

  • 121
  • 7
  • 6
  • 5
  • 5
  • 4
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Dieser H2AFX Antikörper ist unkonjugiert

Applikation

  • 139
  • 56
  • 48
  • 44
  • 33
  • 29
  • 27
  • 24
  • 16
  • 15
  • 8
  • 4
  • 4
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Immunohistochemistry (IHC), ELISA
  • Bindungsspezifität

    • 44
    • 20
    • 18
    • 11
    • 6
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-143

    Kreuzreaktivität

    Human

    Aufreinigung

    Antigen Affinity Purified

    Immunogen

    Recombinant Human Histone H2AX protein (1-143AA)

    Isotyp

    IgG
  • Applikationshinweise

    Recommended dilution: IHC:1:20-1:200,

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C,-80 °C

    Informationen zur Lagerung

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target

    H2AFX (H2A Histone Family, Member X (H2AFX))

    Andere Bezeichnung

    H2AFX

    Hintergrund

    Background: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation.

    Aliases: H2A histone family member X antibody, H2A histone family member X antibody, H2A.FX antibody, H2A.X antibody, H2a/x antibody, H2AFX antibody, H2AX antibody, H2AX_HUMAN antibody, Histone H2A.X antibody

    UniProt

    P16104

    Pathways

    Telomere Maintenance, DNA Reparatur, Positive Regulation of Response to DNA Damage Stimulus
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