HMGN3 Antikörper (AA 1-77)

Produktnummer ABIN7155196

Dieses Anti-HMGN3-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von HMGN3 in ELISA und IHC. Geeignet für Human.

Kurzübersicht für HMGN3 Antikörper (AA 1-77) (ABIN7155196)

Target: HMGN3 (High Mobility Group Nucleosomal Binding Domain 3 (HMGN3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HMGN3 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktdetails anti-HMGN3 Antikörper

Bindungsspezifität: AA 1-77

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human High mobility group nucleosome-binding domain-containing protein 3 protein (1-77AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu HMGN3

Target: HMGN3 (High Mobility Group Nucleosomal Binding Domain 3 (HMGN3))

Andere Bezeichnung: HMGN3

Hintergrund:

Background: Binds to nucleosomes, regulating chromatin structure and consequently, chromatin-dependent processes such as transcription, DNA replication and DNA repair. Affects both insulin and glucagon levels and modulates the expression of pancreatic genes involved in insulin secretion. Regulates the expression of the glucose transporter SLC2A2 by binding specifically to its promoter region and recruiting PDX1 and additional transcription factors. Regulates the expression of SLC6A9, a glycine transporter which regulates the glycine concentration in synaptic junctions in the central nervous system, by binding to its transcription start site. May play a role in ocular development and astrocyte function (By similarity).

Aliases: DKFZp686E20226 antibody, FLJ42187 antibody, High mobility group nucleosomal binding domain 3 antibody, High mobility group nucleosome-binding domain-containing protein 3 antibody, HMGN3 antibody, HMGN3_HUMAN antibody, OTTHUMP00000016772 antibody, OTTHUMP00000016773 antibody, PNAS 24 antibody, PNAS 25 antibody, PNAS24 antibody, PNAS25 antibody, Thyroid hormone receptor interacting protein 7 antibody, Thyroid receptor-interacting protein 7 antibody, TR-interacting protein 7 antibody, TRIP 7 antibody, TRIP-7 antibody, TRIP7 antibody

UniProt: Q15651