This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This HMGN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human HMGN3.
Trip7 antikoerper, PNAS-25 antikoerper, TRIP7 antikoerper, 1110002A15Rik antikoerper, 6330514M13Rik antikoerper, BB071015 antikoerper, high mobility group nucleosomal binding domain 3 L homeolog antikoerper, high mobility group nucleosomal binding domain 3 antikoerper, hmgn3.L antikoerper, HMGN3 antikoerper, Hmgn3 antikoerper
Hintergrund
Thyroid hormone receptors are hormone-dependent transcription factors that regulate expression of a variety of specific target genes. The protein encoded by this gene binds thyroid hormone receptor beta, but only in the presence of thyroid hormone. The encoded protein, a member of the HMGN protein family, is thought to reduce the compactness of the chromatin fiber in nucleosomes, thereby enhancing transcription from chromatin templates. Two transcript variants encoding different isoforms have been found for this gene.