FOXA3 Antikörper (AA 220-336) (HRP)

Produktnummer ABIN7155058

Dieses Anti-FOXA3-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von FOXA3 in ELISA. Geeignet für Human.

Kurzübersicht für FOXA3 Antikörper (AA 220-336) (HRP) (ABIN7155058)

Target: FOXA3 (Forkhead Box A3 (FOXA3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FOXA3 Antikörper ist konjugiert mit HRP

Applikation: ELISA

Produktdetails anti-FOXA3 Antikörper (HRP)

Bindungsspezifität: AA 220-336

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Hepatocyte nuclear factor 3-gamma protein (220-336AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu FOXA3

Target: FOXA3 (Forkhead Box A3 (FOXA3))

Andere Bezeichnung: FOXA3

Hintergrund:

Background: Transcription factor that is thought to act as a \'pioneer\' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites (By similarity). Originally described as a transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Interacts with the cis-acting regulatory regions of these genes. Involved in glucose homeostasis, binds to and activates transcription from the G6PC promoter. Binds to the CYP3A4 promoter and activates its transcription in cooperation with CEBPA. Binds to the CYP3A7 promoter together with members of the CTF/NF-I family. Involved in regulation of neuronal-specific transcription. May be involved in regulation of spermatogenesis.

Aliases: FKHH3 antibody, Fork head-related protein FKH H3 antibody, forkhead box A3 antibody, Forkhead box protein A3 antibody, Foxa3 antibody, FOXA3_HUMAN antibody, hepatic nuclear factor-3-beta antibody, hepatocyte nuclear factor 3 antibody, hepatocyte nuclear factor 3 gamma antibody, Hepatocyte nuclear factor 3-gamma antibody, HNF-3-gamma antibody, HNF-3G antibody, HNF3B antibody, HNF3G antibody, TCF-3G antibody, TCF3G antibody, Transcription factor 3G antibody

UniProt: P55318

Pathways: Carbohydrate Homeostasis