FOXA3 Antikörper (C-Term)

Produktnummer ABIN2779850

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch FOXA3 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd und Schwein.

Kurzübersicht für FOXA3 Antikörper (C-Term) (ABIN2779850)

Target: FOXA3 (Forkhead Box A3 (FOXA3))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FOXA3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-FOXA3 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: Foxa3 Antibody - C-terminal region

Sequenz: YNFNHPFSIN NLMSEQTSTP SKLDVGFGGY GAESGEPGVY YQSLYSRSLL

Homologie: Cow: 86%, Dog: 79%, Guinea Pig: 79%, Horse: 86%, Human: 86%, Mouse: 100%, Pig: 86%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against Foxa3. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the c terminal region of mouse Foxa3

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP36881-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu FOXA3

Target: FOXA3 (Forkhead Box A3 (FOXA3))

Andere Bezeichnung: Foxa3

Hintergrund:

Background Information: Foxa3 is a transcription factor that is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. Foxa3 is originally described as a transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Foxa3 interacts with the cis-acting regulatory regions of these genes.Foxa3 is involved in glucose homeostasis, activates GLUT2 transcription and regulation of neuronal-specific transcription. Foxa3 is also involved in regulation of spermatogenesis, required for the maintenance of the testicular germ cell population and male fertility.

Gene Name: Forkhead box A3

Alternative Symbols: Hnf3, Hnf-3, Hnf3g, Tcf3g, Hnf-3g, Tcf-3g

Protein Name: Hepatocyte nuclear factor 3-gamma

Molekulargewicht: 37kDa

Gen-ID: 15377

NCBI Accession: NP_032286

UniProt: P35584

Pathways: Carbohydrate Homeostasis