TSC1 Antikörper (AA 101-344)
Kurzübersicht für TSC1 Antikörper (AA 101-344) (ABIN7154826)
Target
Alle TSC1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 101-344
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Kreuzreaktivität
- Human
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Aufreinigung
- >95%, Protein G purified
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Immunogen
- Recombinant Human Hamartin protein (101-344AA)
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Isotyp
- IgG
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Applikationshinweise
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- TSC1 (Tuberous Sclerosis 1 (TSC1))
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Andere Bezeichnung
- TSC1
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Hintergrund
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Background: In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Seems not to be required for TSC2 GAP activity towards RHEB. Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling.
Aliases: Hamartin antibody, kiaa0243 antibody, LAM antibody, TSC antibody, Tsc1 antibody, Tsc1 gene antibody, TSC1_HUMAN antibody, Tuberous sclerosis 1 antibody, Tuberous sclerosis 1 protein antibody, tumor suppressor antibody
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UniProt
- Q92574
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Pathways
- RTK Signalweg, AMPK Signaling, Regulation of Cell Size, Tube Formation
Target
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