DKC1 Antikörper (AA 94-170) (FITC)
Kurzübersicht für DKC1 Antikörper (AA 94-170) (FITC) (ABIN7154812)
Target
Alle DKC1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 94-170
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Kreuzreaktivität
- Human
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Aufreinigung
- >95%, Protein G purified
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Immunogen
- Recombinant Human H/ACA ribonucleoprotein complex subunit 4 protein (94-170AA)
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Isotyp
- IgG
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- DKC1 (Dyskeratosis Congenita 1, Dyskerin (DKC1))
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Andere Bezeichnung
- DKC1
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Hintergrund
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Background: Required for ribosome biogenesis and telomere maintenance. Probable catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine (\'psi\') residues, which may serve to stabilize the conformation of rRNAs. Also required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme.
Aliases: CBF5 antibody, CBF5 homolog antibody, Cbf5p homolog antibody, DKC 1 antibody, DKC antibody, Dkc1 antibody, DKC1_HUMAN antibody, DKCX antibody, Dyskeratosis congenita 1 antibody, Dyskeratosis congenita 1 dyskerin antibody, Dyskerin antibody, H/ACA ribonucleoprotein complex subunit 4 antibody, NAP 57 antibody, NAP57 antibody, NOLA 4 antibody, NOLA4 antibody, Nopp140 associated protein of 57 kDa antibody, Nopp140-associated protein of 57 kDa antibody, Nucleolar protein family A member 4 antibody, Nucleolar protein NAP57 antibody, snoRNP protein DKC1 antibody, XAP 101 antibody, XAP101 antibody
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UniProt
- O60832
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Pathways
- Telomere Maintenance
Target
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