GNL3L Antikörper (AA 1-582) (Biotin)
Kurzübersicht für GNL3L Antikörper (AA 1-582) (Biotin) (ABIN7154758)
Target
Alle GNL3L Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1-582
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Kreuzreaktivität
- Human
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Aufreinigung
- >95%, Protein G purified
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Immunogen
- Recombinant Human Guanine nucleotide-binding protein-like 3-like protein (1-582AA)
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Isotyp
- IgG
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- GNL3L (Guanine Nucleotide Binding Protein-Like 3 (Nucleolar)-Like (GNL3L))
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Andere Bezeichnung
- GNL3L
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Hintergrund
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Background: Stabilizes TERF1 telomeric association by preventing TERF1 recruitment by PML. Stabilizes TERF1 protein by preventing its ubiquitination and hence proteasomal degradation. Does so by interfering with TERF1-binding to FBXO4 E3 ubiquitin-protein ligase. Required for cell proliferation. By stabilizing TRF1 protein during mitosis, promotes metaphase-to-anaphase transition. Stabilizes MDM2 protein by preventing its ubiquitination, and hence proteasomal degradation. By acting on MDM2, may affect TP53 activity. Required for normal processing of ribosomal pre-rRNA. Binds GTP.
Aliases: GNL3LGuanine nucleotide-binding protein-like 3-like protein antibody
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UniProt
- Q9NVN8
Target
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