GNL3L Antikörper

Produktnummer ABIN6258968

Produktdetails anti-GNL3L Antikörper

Target: GNL3L (Guanine Nucleotide Binding Protein-Like 3 (Nucleolar)-Like (GNL3L))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GNL3L Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: GNL3L Antibody detects endogenous levels of total GNL3L

Kreuzreaktivität: Human

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500~1:1000, IF/ICC 1:100-1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C.Stable for 12 months from date of receipt

Haltbarkeit: 12 months

Details zu GNL3L

Target: GNL3L (Guanine Nucleotide Binding Protein-Like 3 (Nucleolar)-Like (GNL3L))

Andere Bezeichnung: GNL3L (GNL3L Produkte)

Synonyme: SI:zK13A21.8 antikoerper, flj10613 antikoerper, flj10613l antikoerper, si:dkey-13a21.8 antikoerper, zgc:110536 antikoerper, BC020354 antikoerper, guanine nucleotide binding protein-like 3 (nucleolar)-like antikoerper, guanine nucleotide binding protein-like 3 (nucleolar)-like S homeolog antikoerper, G protein nucleolar 3 like antikoerper, gnl3l antikoerper, gnl3l.S antikoerper, GNL3L antikoerper, Gnl3l antikoerper

Hintergrund:

Description: Stabilizes TERF1 telomeric association by preventing TERF1 recruitment by PML. Stabilizes TERF1 protein by preventing its ubiquitination and hence proteasomal degradation. Does so by interfering with TERF1-binding to FBXO4 E3 ubiquitin-protein ligase. Required for cell proliferation. By stabilizing TRF1 protein during mitosis, promotes metaphase-to-anaphase transition. Stabilizes MDM2 protein by preventing its ubiquitination, and hence proteasomal degradation. By acting on MDM2, may affect TP53 activity. Required for normal processing of ribosomal pre-rRNA. Binds GTP.

Gene: GNL3L

Molekulargewicht: 66 kDa

Gen-ID: 54552

UniProt: Q9NVN8