GAPDH Antikörper (AA 2-335) (FITC)

Produktnummer ABIN7154136

Produktdetails anti-GAPDH Antikörper (FITC)

Target: GAPDH (Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH))

Bindungsspezifität: AA 2-335

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GAPDH Antikörper ist konjugiert mit FITC

Applikation: Bitte anfragen

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Glyceraldehyde-3-phosphate dehydrogenase protein (2-335AA)

Isotyp: IgG

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu GAPDH

Target: GAPDH (Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH))

Andere Bezeichnung: GAPDH (GAPDH Produkte)

Hintergrund:

Background: Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubules (By similarity). Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma treatment assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3\'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation.

Aliases: 38 kDa BFA-dependent ADP-ribosylation substrate antibody, aging associated gene 9 protein antibody, Aging-associated gene 9 protein antibody, BARS-38 antibody, cb609 antibody, EC 1.2.1.12 antibody, Epididymis secretory sperm binding protein Li 162eP antibody, G3P_HUMAN antibody, G3PD antibody, G3PDH antibody, GAPD antibody, GAPDH antibody, Glyceraldehyde 3 phosphate dehydrogenase antibody, glyceraldehyde 3-PDH antibody, Glyceraldehyde-3-phosphate dehydrogenase antibody, HEL-S-162eP antibody, KNC-NDS6 antibody, MGC102544 antibody, MGC102546 antibody, MGC103190 antibody, MGC103191 antibody, MGC105239 antibody, MGC127711 antibody, MGC88685 antibody, OCAS, p38 component antibody, OCT1 coactivator in S phase, 38-KD component antibody, peptidyl cysteine S nitrosylase GAPDH antibody, Peptidyl-cysteine S-nitrosylase GAPDH antibody, wu:fb33a10 antibody

UniProt: P04406