FBP1 Antikörper (AA 1-338)

Produktnummer ABIN7153202

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch FBP1 in ELISA und IHC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für FBP1 Antikörper (AA 1-338) (ABIN7153202)

Target: FBP1 (Fructose-1,6-Bisphosphatase 1 (FBP1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FBP1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktdetails anti-FBP1 Antikörper

Bindungsspezifität: AA 1-338

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Fructose-1,6-bisphosphatase 1 protein (1-338AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu FBP1

Target: FBP1 (Fructose-1,6-Bisphosphatase 1 (FBP1))

Andere Bezeichnung: FBP1

Hintergrund:

Background: Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations, acting as a rate-limiting enzyme in gluconeogenesis. Plays a role in regulating glucose sensing and insulin secretion of pancreatic beta-cells. Appears to modulate glycerol gluconeogenesis in liver. Important regulator of appetite and adiposity, increased expression of the protein in liver after nutrient excess increases circulating satiety hormones and reduces appetite-stimulating neuropeptides and thus seems to provide a feedback mechanism to limit weight gain.

Aliases: 6-bisphosphatase 1 antibody, 6-bisphosphate 1-phosphohydrolase 1 antibody, D fructose 1 6 bisphosphate 1 phosphohydrolase 1 antibody, D-fructose-1 antibody, EC 3.1.3.11 antibody, F16P1_HUMAN antibody, FBP antibody, FBP 1 antibody, FBP1 antibody, FBPase 1 antibody, Fructose 1 6 bisphosphatase 1 antibody, Fructose bisphosphatase 1 antibody, Fructose-1 antibody, Growth inhibiting protein 17 antibody, Liver fructose bisphosphatase antibody

UniProt: P09467

Pathways: Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Dicarboxylic Acid Transport